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BATTINELLI LAB
2023

Lucas, F., Lewis, J., Grandoni, J., Sylvester, K. W., Bernier, T. D., Ting, C., Sek, R., Ballard, K., Connors, J. M., & Battinelli, E. M. (2023). One-year retrospective analysis of anti-FXa apixaban and rivaroxaban levels demonstrates utility for management decisions in various urgent and nonurgent clinical situations. American Journal of Clinical Pathology, aqad085. Advance online publication. https://doi.org/10.1093/ajcp/aqad085

Avila, J., Degirmenci, H. B., Contreras Chavez, P., Battinelli, E. M., & Fleisher, J. (2023). Rapid Onset Severe Immune Thrombocytopenia following mRNA COVID-19 Vaccine in a Young Patient. Case reports in hematology, 2023, 7877536. https://doi.org/10.1155/2023/7877536

Roweth, H. G., & Battinelli, E. M. (2023). Platelets and (Lymph)angiogenesis. Cold Spring Harbor perspectives in medicine, 13(1), a041174. https://doi.org/10.1101/cshperspect.a041174

2022

Roweth, H. G., Malloy, M. W., Goreczny, G. J., Becker, I. C., Guo, Q., Mittendorf, E. A., Italiano, J. E., Jr, McAllister, S. S., & Battinelli, E. M. (2022). Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer. Science advances, 8(41), eabo5224. https://doi.org/10.1126/sciadv.abo5224

Gawelek, K. L., Padera, R., Connors, J., Pinkus, G. S., Podznyakova, O., & Battinelli, E. M. (2022). Cardiac megakaryocytes in SARS-CoV-2-positive autopsies. Histopathology, 81(5), 600–624. https://doi.org/10.1111/his.14734

Guo, Q., Malloy, M. W., Roweth, H. G., McAllister, S. S., Italiano, J. E., & Battinelli, E. M. (2022). Platelets upregulate tumor cell programmed death ligand 1 in an epidermal growth factor receptor-dependent manner in vitro. Blood advances, 6(20), 5668–5675. https://doi.org/10.1182/bloodadvances.2021006120

2021

Lucas, F., Stecker, M. S., Pozdnyakova, O., Connors, J. M., & Battinelli, E. M. (2021). Rivaroxaban-calibrated chromogenic anti-Xa assay in cirrhosis: Use to rule out disseminated intravascular coagulation. Research and practice in thrombosis and haemostasis, 5(7), e12594. https://doi.org/10.1002/rth2.12594

Gawelek, K. L., & Battinelli, E. M. (2021). Are Platelets SARS-CoV-2’s “Dead End”?. Circulation research, 129(6), 647–649. https://doi.org/10.1161/CIRCRESAHA.121.319913

Tsai, F. D., & Battinelli, E. M. (2021). Inherited Platelet Disorders. Hematology/oncology clinics of North America, 35(6), 1069–1084. https://doi.org/10.1016/j.hoc.2021.07.003

Roweth, H. G., & Battinelli, E. M. (2021). Lessons to learn from tumor-educated platelets. Blood, 137(23), 3174–3180. https://doi.org/10.1182/blood.2019003976

Alba, G. A., Samokhin, A. O., Wang, R. S., Zhang, Y. Y., Wertheim, B. M., Arons, E., Greenfield, E. A., Lundberg Slingsby, M. H., Ceglowski, J. R., Haley, K. J., Bowman, F. P., Yu, Y. R., Haney, J. C., Eng, G., Mitchell, R. N., Sheets, A., Vargas, S. O., Seo, S., Channick, R. N., Leary, P. J., … Maron, B. A. (2021). NEDD9 Is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation. American journal of respiratory and critical care medicine, 203(12), 1533–1545. https://doi.org/10.1164/rccm.202003-0719OC

Pozdnyakova, O., Connell, N. T., Battinelli, E. M., Connors, J. M., Fell, G., & Kim, A. S. (2021). Clinical Significance of CBC and WBC Morphology in the Diagnosis and Clinical Course of COVID-19 Infection. American journal of clinical pathology, 155(3), 364–375. https://doi.org/10.1093/ajcp/aqaa231

2020

Battinelli E. M. (2020). COVID-19 concerns aggregate around platelets. Blood, 136(11), 1221–1223. https://doi.org/10.1182/blood.2020007805

Chen, E. C., Zon, R. L., Battinelli, E. M., & Connors, J. M. (2020). Approach to the Patient with COVID-19-Associated Thrombosis: A Case-Based Review. The oncologist, 25(10), e1500–e1508. https://doi.org/10.1634/theoncologist.2020-0682

Connell, N. T., Battinelli, E. M., & Connors, J. M. (2020). Coagulopathy of COVID-19 and antiphospholipid antibodies. Journal of thrombosis and haemostasis : JTH, 18(9), E1–E2. https://doi.org/10.1111/jth.14893

2019

Battinelli, E. M., Thon, J. N., Okazaki, R., Peters, C. G., Vijey, P., Wilkie, A. R., Noetzli, L. J., Flaumenhaft, R., & Italiano, J. E. (2019). Megakaryocytes package contents into separate α-granules that are differentially distributed in platelets. Blood advances, 3(20), 3092–3098. https://doi.org/10.1182/bloodadvances.2018020834

Johnson, K. E., Ceglowski, J. R., Roweth, H. G., Forward, J. A., Tippy, M. D., El-Husayni, S., Kulenthirarajan, R., Malloy, M. W., Machlus, K. R., Chen, W. Y., Italiano, J. E., Jr, & Battinelli, E. M. (2019). Aspirin inhibits platelets from reprogramming breast tumor cells and promoting metastasis. Blood advances, 3(2), 198–211. https://doi.org/10.1182/bloodadvances.2018026161

Hall, K. T., Buring, J. E., Mukamal, K. J., Vinayaga Moorthy, M., Wayne, P. M., Kaptchuk, T. J., Battinelli, E. M., Ridker, P. M., Sesso, H. D., Weinstein, S. J., Albanes, D., Cook, N. R., & Chasman, D. I. (2019). COMT and Alpha-Tocopherol Effects in Cancer Prevention: Gene-Supplement Interactions in Two Randomized Clinical Trials. Journal of the National Cancer Institute, 111(7), 684–694. https://doi.org/10.1093/jnci/djy204

2018

Takagi, S., Tsukamoto, S., Park, J., Johnson, K. E., Kawano, Y., Moschetta, M., Liu, C. J., Mishima, Y., Kokubun, K., Manier, S., Salem, K. Z., Huynh, D., Sacco, A., Forward, J., Roccaro, A. M., Battinelli, E. M., & Ghobrial, I. M. (2018). Platelets Enhance Multiple Myeloma Progression via IL-1β Upregulation. Clinical cancer research : an official journal of the American Association for Cancer Research, 24(10), 2430–2439. https://doi.org/10.1158/1078-0432.CCR-17-2003

Simmons, D. P., Herskovits, A. Z., Battinelli, E. M., Schur, P. H., Lemire, S. J., & Dorfman, D. M. (2018). Lupus anticoagulant testing using two parallel methods detects additional cases and predicts persistent positivity. Clinical chemistry and laboratory medicine, 56(8), 1289–1296. https://doi.org/10.1515/cclm-2015-0790

2017

Machlus, K. R., & Battinelli, E. M. (2017). RBCs pin platelets against the (thrombus) wall. Blood, 129(18), 2460–2461. https://doi.org/10.1182/blood-2017-03-772079

Johnson, K. E., Forward, J. A., Tippy, M. D., Ceglowski, J. R., El-Husayni, S., Kulenthirarajan, R., Machlus, K. R., Mayer, E. L., Italiano, J. E., Jr, & Battinelli, E. M. (2017). Tamoxifen Directly Inhibits Platelet Angiogenic Potential and Platelet-Mediated Metastasis. Arteriosclerosis, thrombosis, and vascular biology, 37(4), 664–674. https://doi.org/10.1161/ATVBAHA.116.308791

2016

Hollenhorst, M. A., & Battinelli, E. M. (2016). Thrombosis, Hypercoagulable States, and Anticoagulants. Primary care, 43(4), 619–635. https://doi.org/10.1016/j.pop.2016.07.001

Machlus, K. R., Johnson, K. E., Kulenthirarajan, R., Forward, J. A., Tippy, M. D., Soussou, T. S., El-Husayni, S. H., Wu, S. K., Wang, S., Watnick, R. S., Italiano, J. E., Jr, & Battinelli, E. M. (2016). CCL5 derived from platelets increases megakaryocyte proplatelet formation. Blood, 127(7), 921–926. https://doi.org/10.1182/blood-2015-05-644583

2015

Battinelli E. M. (2015). Procoagulant Platelets: Not Just Full of Hot Air. Circulation, 132(15), 1374–1376. https://doi.org/10.1161/CIRCULATIONAHA.115.018833

2014

Battinelli E. M. (2014). TTP and pregnancy. Blood, 123(11), 1624–1625. https://doi.org/10.1182/blood-2014-01-549469

Battinelli, E. M., Markens, B. A., Kulenthirarajan, R. A., Machlus, K. R., Flaumenhaft, R., & Italiano, J. E., Jr (2014). Anticoagulation inhibits tumor cell-mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response. Blood, 123(1), 101–112. https://doi.org/10.1182/blood-2013-02-485011

2013

Battinelli, E. M., Marshall, A., & Connors, J. M. (2013). The role of thrombophilia in pregnancy. Thrombosis, 2013, 516420. https://doi.org/10.1155/2013/516420

2012

Kuznetsov, H. S., Marsh, T., Markens, B. A., Castaño, Z., Greene-Colozzi, A., Hay, S. A., Brown, V. E., Richardson, A. L., Signoretti, S., Battinelli, E. M., & McAllister, S. S. (2012). Identification of luminal breast cancers that establish a tumor-supportive macroenvironment defined by proangiogenic platelets and bone marrow-derived cells. Cancer discovery, 2(12), 1150–1165. https://doi.org/10.1158/2159-8290.CD-12-0216

Battinelli, E. M., Murphy, D. L., & Connors, J. M. (2012). Venous thromboembolism overview. Hematology/oncology clinics of North America, 26(2), 345–ix. https://doi.org/10.1016/j.hoc.2012.02.010

2011

Battinelli E. M. (2011). Reversal of new oral anticoagulants. Circulation, 124(14), 1508–1510. https://doi.org/10.1161/CIRCULATIONAHA.111.054510

Battinelli, E. M., Markens, B. A., & Italiano, J. E., Jr (2011). Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis. Blood, 118(5), 1359–1369. https://doi.org/10.1182/blood-2011-02-334524

Battinelli, E. M., & Bauer, K. A. (2011). Thrombophilias in pregnancy. Hematology/oncology clinics of North America, 25(2), 323–viii. https://doi.org/10.1016/j.hoc.2011.02.003

2009

Italiano, J. E., Jr, & Battinelli, E. M. (2009). Selective sorting of alpha-granule proteins. Journal of thrombosis and haemostasis : JTH, 7 Suppl 1(Suppl 1), 173–176. https://doi.org/10.1111/j.1538-7836.2009.03387.x

Before 2008

Battinelli, E. M., Hartwig, J. H., & Italiano, J. E., Jr (2007). Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis. Current opinion in hematology, 14(5), 419–426. https://doi.org/10.1097/MOH.0b013e3282bad151

Battinelli, E. M., & Ansell, J. (2005). Cancer and thrombosis. Current hematology reports, 4(5), 378–384.

Freedman, J. E., Sauter, R., Battinelli, E. M., Ault, K., Knowles, C., Huang, P. L., & Loscalzo, J. (1999). Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. Circulation research, 84(12), 1416–1421. https://doi.org/10.1161/01.res.84.12.1416

Battinelli, E. M., Boyd, Y., Craig, I. W., Breakefield, X. O., & Chen, Z. Y. (1996). Characterization and mapping of the mouse NDP (Norrie disease) locus (Ndp). Mammalian genome : official journal of the International Mammalian Genome Society, 7(2), 93–97. https://doi.org/10.1007/s003359900026

Chen, Z. Y., Battinelli, E. M., Woodruff, G., Young, I., Breakefield, X. O., & Craig, I. W. (1993). Characterization of a mutation within the NDP gene in a family with a manifesting female carrier. Human molecular genetics, 2(10), 1727–1729. https://doi.org/10.1093/hmg/2.10.1727

Chen, Z. Y., Battinelli, E. M., Fielder, A., Bundey, S., Sims, K., Breakefield, X. O., & Craig, I. W. (1993). A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy. Nature genetics, 5(2), 180–183. https://doi.org/10.1038/ng1093-180

Chen, Z. Y., Battinelli, E. M., Hendriks, R. W., Powell, J. F., Middleton-Price, H., Sims, K. B., Breakefield, X. O., & Craig, I. W. (1993). Norrie disease gene: characterization of deletions and possible function. Genomics, 16(2), 533–535. https://doi.org/10.1006/geno.1993.1224 

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